2024 PN NCLEX Questions Nursing Practice Question
Some drugs are excreted into bile and delivered to the intestines. Prior to elimination from the body, the drug might be absorbed. This process is known as:
Correct Answer: C
Rationale: The process described involves drugs being secreted into bile, then reaching the intestines where they may be reabsorbed before elimination. This is known as enterohepatic cycling, as it refers to the circulation of substances from the liver to the intestines and back.
Option A, hepatic clearance, pertains to the liver's ability to remove drugs from the bloodstream, not their recycling. Option B, total clearance, refers to the overall elimination of a drug from the body, encompassing all routes, but does not specifically address the reabsorption process. Option D, first-pass effect, describes the metabolism of a drug in the liver before it enters systemic circulation, which is unrelated to the recycling aspect of enterohepatic cycling.