Pharmacy Technician Certification Exam Practice Question
An interaction with calcium may cause a decrease in the therapeutic effect of which of the following medications?
Correct Answer: B
Rationale: Calcium can bind to certain medications, affecting their absorption and effectiveness. Doxycycline, a tetracycline antibiotic, is known to form insoluble complexes with calcium, leading to decreased therapeutic effects.
Azithromycin and erythromycin, both macrolide antibiotics, do not have significant interactions with calcium that affect their efficacy. Doxylamine, an antihistamine, is also not impacted by calcium in this way. Thus, while doxycycline's absorption is compromised by calcium, the other options remain unaffected, making doxycycline the only medication in this list whose therapeutic effect is diminished by calcium interaction.
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