2024 PN NCLEX Questions Nursing Practice Question

Which of the following clients should refrain from therapy with the thiazide diuretic hydrochlorothiazide (HCTZ)?

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Correct Answer: C

Rationale: Hydrochlorothiazide (HCTZ) can be problematic for clients with diabetes mellitus, type II, as it may elevate blood glucose levels, complicating glycemic control.

Option A, a client with renal impairment, may still benefit from HCTZ under careful monitoring, as it can help manage fluid balance. Option B, a client with hypertension, is often treated with HCTZ, which effectively lowers blood pressure. Option D, a client with renal calculi, may actually benefit from HCTZ, as it can help reduce calcium excretion in urine, potentially preventing kidney stone formation. Thus, option C poses the greatest risk for adverse effects.