2024 PN NCLEX Questions Nursing Practice Question
What effect can medication bound to protein have?
Correct Answer: C
Rationale: Medication bound to protein affects its availability to produce desired medicinal effects. When drugs are bound to proteins in the bloodstream, only the unbound (free) fraction can exert therapeutic effects.
Option A is misleading; while protein binding can reduce the free drug concentration, it does not directly equate to reduced availability in all contexts. Option B is partially correct but too narrow; while protein binding can limit distribution, it primarily impacts the drug's effectiveness rather than just distribution. Option D is incorrect as protein binding typically does not decrease metabolism; rather, it may alter the rate of metabolism depending on the drug's characteristics.