2024 PN NCLEX Questions Nursing Practice Question

The physician orders the antibiotics ampicillin (Omnipen) and gentamicin (Garamycin) for a newly admitted client with an infection. The nurse should:

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Correct Answer: B

Rationale: Administering ampicillin and gentamicin sequentially with proper flushing is essential to prevent potential drug interactions and ensure effective delivery. Gentamicin, an aminoglycoside, can be inactivated by certain beta-lactam antibiotics like ampicillin when mixed, making flushing between medications necessary.

Option A is incorrect as administering both simultaneously risks inactivation of gentamicin. Option C, while cautious, does not provide the nurse with a clear protocol for administration. Option D delays treatment unnecessarily, potentially compromising patient care when both antibiotics can be safely administered in sequence.