Pharmacy Technician Certification Board Practice Exam Practice Question

Which of the following medications is most likely to decrease the effectiveness of oral birth control pills?

Correct Answer: A

Rationale: Rifampin is a potent inducer of liver enzymes, particularly cytochrome P450, which accelerates the metabolism of estrogen and progestin in oral contraceptives, thereby reducing their effectiveness.

Carisoprodol, a muscle relaxant, does not significantly interact with the metabolism of birth control pills and is unlikely to affect their efficacy.

Sertraline, an antidepressant, has minimal impact on hormonal contraceptives and is generally considered safe to use concurrently.

Atorvastatin, a cholesterol-lowering medication, also does not interfere with the effectiveness of oral contraceptives.

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