Pharmacy Technician Certification Exam Practice Questions Practice Question
Which of the following medications is known to have a narrow therapeutic index?
Correct Answer: A
Rationale: Tacrolimus is recognized for its narrow therapeutic index, meaning that small changes in dosage can lead to significant variations in drug effects and toxicity. This necessitates careful monitoring of blood levels to avoid adverse effects, particularly in transplant patients.
Tolterodine, primarily used for overactive bladder, has a wider therapeutic range and does not require such stringent monitoring. Travoprost, an eye drop for glaucoma, also has a broad safety margin. Tadalafil, used for erectile dysfunction and pulmonary hypertension, is effective within a wider dosage range, making it less risky in terms of therapeutic index.
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