Free NCLEX-PN Practice Questions Practice Question
The nurse is discussing hemophilia with a group of parents. Which child is most likely to have classic hemophilia?
Correct Answer: A
Rationale: Classic hemophilia, primarily caused by a deficiency in factor VIII, is an X-linked recessive disorder. Males are more affected due to having only one X chromosome.
A male whose mother is a carrier (Option A) has a 50% chance of inheriting the affected X chromosome, making him the most likely candidate for classic hemophilia.
Option B is incorrect; a male cannot inherit hemophilia from his father, as males pass on their Y chromosome to sons.
Option C involves a female, who may be a carrier but is less likely to exhibit symptoms unless she inherits the affected X from both parents.
Option D is also incorrect; while a female can inherit hemophilia from an affected father, she would need to inherit a second affected X chromosome from her mother to express the disease.
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