NCLEX PN Practice Test Practice Question
An adult is prescribed lovastatin (Mevacor). The nurse should teach the client that while he is taking lovastatin (Mevacor), he must avoid:
Correct Answer: B
Rationale: Lovastatin (Mevacor) is metabolized by the liver, specifically by the cytochrome P450 enzyme system. Grapefruit juice inhibits this enzyme, potentially increasing lovastatin levels in the blood and heightening the risk of side effects, such as muscle damage.
Eating apples (A) poses no known interaction with lovastatin. Using aspirin (C) and ibuprofen (D) is generally safe, though they should be used cautiously in patients with certain conditions. Therefore, avoiding grapefruit juice is crucial to ensure the medication's effectiveness and safety.
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